Chronic kidney disease (CKD):
CKD leads to A progressive loss of glomerular function. It is present when the glomerular filtration rate (GFR) is less than 60 ml/min/1.73 m2. This should be present for three consecutive months or greater. It may require dialysis.
Basic kidney Functions
- Filteration of the blood products
- Regulation of blood pressure
- Regulates body fluid volume
- Production of rbc
Risk Factors for CKD-
- Older age
- More in males
- Presence of systemic hypertension, obesity, smoking proteinuria, dyslipidemia, etc
Classification-
- stage 1: normal or elevated GFR
- 2: mild reduction in GFR
- 3: moderate reduction in GFR
- 4: severe reduction in GFR
- 5: dialysis/ end-stage kidney disease
Clinical Presentation-
- cola coloured urine (due to RBC casts)
- nausea, vomiting, weight loss
- muscle loss/ sarcopenia
Acute Renal Failure (ARF)
the glomerular filtration declines abruptly (hours to days) and is usually reversible. AKI diagnosis is done with any one of the following:
(1) creatinine more than 0.3 mg/dL in 48 hours
(2) creatinine increase to 1.5 times of baseline value within last 7 days,
(3) urine volume <0.5 mL/kg/hour for 6 hours.
Chronic Renal Failure (CRF)
CRF represents a persistent impairment of kidney function. There is an abnormally elevated serum creatinine for more than 3 months.It often involves a progressive loss of kidney function. Crf is a condition usually necessitating renal replacement therapy.
Also read- https://vcurehealthcare.com/myasthenia-gravis-features-treatment-and-more/
